Molecular Formula | C18H20ClN3O3 |
Molar Mass | 361.82 |
Density | 1.22±0.1 g/cm3(Predicted) |
Melting Point | 97 - 99°C |
Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
Appearance | neat |
Color | White to Off-White |
pKa | 11.51±0.46(Predicted) |
Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
In vitro study | Pyribencarb potently inhibits succinate-cytochrome c reductase (SCR) activities of Botrytis cinerea (cucumber gray mold), Corynespora cassiicola (leaf spot) and decylubiquinol-cytochrome c reductase (UCR) activity of B. cinerea . Pyribencarb inhibits the UCR of B. cinerea in an uncompetitive manner, and the substrate-dependent inhibition constant is found from calculation to be 13 nM. The target site of Pyribencarb is cytochrome b of complex III in the electron transport system of the respiratory chain. The inhibitory potency of pyribencarb on SCR activities of plants, rats and carp is relatively weak compared with that of strobilurin fungicides. |
WGK Germany | 3 |
biological activity | Pyribencarb is a benzyl carbamate fungicide with activity against a variety of phytopathogenic fungi. Pyribencarb is a potent Qo inhibitor of cytochrome B. Pyribencarb is particularly effective against Botrytis cinerea and Sclerotinia sclerotiorum. |